Neuropsychological Effects of Anticonvulsants

Neuropsychological Effects of Anticonvulsants

Investigators from 7 centers in Korea conducted a prospective, multicenter study with patients randomized into two open-label, parallel groups and treated with either levetiracetam (LVT) or carbamazepine (CBZ) monotherapy for newly diagnosed focal epilepsy.

Iatrogenic nutritional effects of anticonvulsants.

The three major anticonvulsants currently used for the treatment of grand ma1 and focal epilepsy are phenobarbitone (introduced into therapy in 1912), diphenylhydantoin (DPII) (introduced in 1938), and primidone (introduced in 1952). Fig. I illustrates the common structural features of these drugs, which presumably account for their common anticonvulsant properties and side-effects. There are s...

Effects of anticonvulsants on the electroencephalogram.

Differential effects of petit mal anticonvulsants and convulsants

1 Currents evoked by applications of y-aminobutyric acid (GABA) to acutely dissociated thalamic neurones were analysed by voltage-clamp techniques, and the effects of the anticonvulsant succinimides ethosuximide (ES) and a-methyl-a-phenylsuccinimide (MPS) and the convulsants tetramethylsuccinimide (TMS), picrotoxin, pentylenetetrazol (PTZ), and bicuculline methiodide were assessed. 2 TMS (1 juM...

Neuropsychological effects of marijuana.

This study assigned 81 non-naïve subjects, divided into low- and high-dose groups, to four experimental conditions (marijuana/marijuana, marijuana/placebo, placebo/marijuana and placebo/placebo) for two sessions separated by about one week. The low dose was 4.8 mg. Delta(9)-THC followed by 2.4 mg. one hour later. The high dose was 9.1 mg. followed by 4.5 mg. one hour later. A battery of neurops...